IV fluid (saline + dextrose)
Sodium chloride with glucose
Adult dose
Dose: 0.9% NaCl + 5% glucose: maintenance 25–30 mL/kg/day adjusted. DKA: glucose-containing once BG <14
Route: IV
Frequency: per indication
Clinical pearls
- Maintenance fluid, paediatric resuscitation (0.9%+5% per APLS)
- DKA secondary fluid once BG <14 mmol/L (JBDS)
Contraindications
- Hyperglycaemia (uncontrolled)
- Hyponatraemia (severe)
- Volume overload
Side effects
- Hyperglycaemia
- Hyponatraemia
- Volume overload
Interactions
- Insulin
- Diuretics
Monitoring
- Na+
- Glucose
Reference: BNF; NICE CG174/NG29; APLS; JBDS; https://bnf.nice.org.uk/drugs/sodium-chloride-with-glucose/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Parkland Formula for Burns Fluid Resuscitation · Burns
- TBSA — Total Body Surface Area Burned (Rule of Nines) · Formula
- HbA1c Converter · Diabetes
- Corrected Sodium (Hyperglycaemia) · Electrolytes
- Glucose Infusion Rate (GIR) Calculator · Glucose Management
- C-Peptide to Glucose Ratio · Diabetes Classification
Pathways
- Sepsis Screening and Sepsis Six · UK Sepsis Trust; NICE NG51; Surviving Sepsis Campaign 2021
- Febrile Child Assessment (Traffic Light) · NICE CG160 2013
- Bronchiolitis Management · NICE NG9 2015
- Paediatric DKA · BSPED 2020
- Seizure Management in Children · NICE CG137 / APLS
- Wheeze and Asthma in Children · BTS/SIGN 2019 / NICE NG80