Non-selective NSAID
Ketoprofen
Brand names: Oruvail, Powergel
Adult dose
Dose: PO 100–200mg/day in divided doses (max 200mg). Topical gel: apply 2–4 times/day
Route: PO/Topical
Frequency: divided
Clinical pearls
- Topical: musculoskeletal pain
- MHRA: topical ketoprofen photosensitivity — avoid sun exposure for 2 weeks after use
Contraindications
- Active GI bleeding/ulcer
- Severe heart failure
- Severe renal impairment
- NSAID hypersensitivity
- 3rd trimester pregnancy
Side effects
- GI upset/bleeding
- Renal impairment
- Cardiovascular events
- Bronchospasm
- Topical: photosensitivity, contact dermatitis
Interactions
- Anticoagulants
- ACEi/ARB
- Lithium
- Methotrexate
Reference: BNF; MHRA Drug Safety Update; https://bnf.nice.org.uk/drugs/ketoprofen/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
Pathways
- Cutaneous Lupus Erythematosus · BAD; EULAR
- Osteoporosis / Fragility Fracture · NOGG 2021; NICE NG147; NG224
- Arteritic AION (Giant Cell Arteritis) · RCOphth; BSR
- Osteoarthritis Hip / Knee Management · NICE NG226 (2022)
- Lupus Nephritis · EULAR/ERA-EDTA 2019; KDIGO 2024
- Rheumatoid Arthritis Management · NICE CG79 2018 / EULAR 2022