haematology anaesthesia-icu
Cryoprecipitate Dose Calculator for Fibrinogen Replacement
Calculates number of cryoprecipitate pools required to raise fibrinogen to target level. Treatment of choice for acquired hypofibrinogenaemia in DIC, massive haemorrhage, obstetric haemorrhage, and liver disease. In the UK each pool contains 5 units; each unit raises plasma fibrinogen approximately 0.1 g/L per 70 kg adult.
References
- NICE NG24. Blood transfusion. NICE. 2015 (updated 2023).
- Hunt BJ et al. A practical guideline for the haematological management of major haemorrhage. Br J Haematol. 2015;170(6):788-803.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Corrected Count Increment (CCI) for Platelet Transfusion · Transfusion Medicine
- ABC Score for Massive Transfusion · Transfusion Medicine
- Maximum Allowable Blood Loss · Transfusion Medicine
- Blood Volume Calculation (Nadler Formula) · Transfusion Medicine
- Sickle Cell Exchange Transfusion Volume · Transfusion Medicine
- Fresh Frozen Plasma (FFP) Dose Calculator · Transfusion Medicine
Drugs
- Fibrinogen Concentrate · Coagulation Factor Replacement — Hypofibrinogenaemia
- Dopamine (ICU — Vasopressor/Inotrope) · Catecholamine (Dose-Dependent Vasopressor/Inotrope)
- Hydroxocobalamin (High-Dose — Cyanide Antidote) · Cyanide Antidote (Vitamin B12 Precursor at High Dose)
- Dopamine hydrochloride · Inotrope / vasopressor (dose-dependent)
- Enalapril with hydrochlorothiazide · ACE inhibitor + thiazide diuretic (fixed-dose)
- Amiloride with Bumetanide · Potassium-Sparing Diuretic + Loop Diuretic (Fixed-Dose Combination)
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.