haematology anaesthesia-icu
Fresh Frozen Plasma (FFP) Dose Calculator
Calculates volume and number of units of fresh frozen plasma required for coagulopathy correction. Each FFP unit in the UK is approximately 280 mL. Standard dose is 12-15 mL/kg for active bleeding with coagulopathy. Note: 4-factor PCC (Beriplex/Octaplex) is preferred over FFP for urgent warfarin reversal.
References
- NICE NG24. Blood transfusion. NICE. 2015 (updated 2023).
- BCSH. Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. Br J Haematol. 2004;126(1):11-28.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Corrected Count Increment (CCI) for Platelet Transfusion · Transfusion Medicine
- ABC Score for Massive Transfusion · Transfusion Medicine
- Maximum Allowable Blood Loss · Transfusion Medicine
- Blood Volume Calculation (Nadler Formula) · Transfusion Medicine
- Sickle Cell Exchange Transfusion Volume · Transfusion Medicine
- Cryoprecipitate Dose Calculator for Fibrinogen Replacement · Transfusion Medicine
Drugs
- Fresh frozen plasma (FFP) · Blood component
- Prothrombin Complex Concentrate (PCC) · Coagulation Factor Concentrate — Warfarin Reversal
- Neostigmine · Anticholinesterase (Reversal Agent)
- Sugammadex · Selective Neuromuscular Blockade Reversal Agent
- Dopamine (ICU — Vasopressor/Inotrope) · Catecholamine (Dose-Dependent Vasopressor/Inotrope)
- Protamine Sulphate · Heparin Reversal Agent
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.