haematology
PLASMIC Score for TTP
Predicts likelihood of ADAMTS13 deficiency (thrombotic thrombocytopenic purpura) in patients with thrombotic microangiopathy to guide urgent plasma exchange.
References
- Bendapudi PK et al. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies. Lancet Haematol. 2017;4(4):e157–e164.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Gelatin (succinylated) · Colloid plasma volume expander
- Lanadelumab · Anti-plasma kallikrein monoclonal antibody
- C1-esterase inhibitor · Plasma-derived complement inhibitor
- Berotralstat · Oral plasma kallikrein inhibitor
- Albumin solution · Plasma derivative / colloid
- Colestyramine (Cholestyramine) · Bile Acid Sequestrant / Ion Exchange Resin
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
- Anticoagulation Reversal · BSH 2016 / ESC
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.