OphthalmologyEmergency Medicine
Chemical Eye Injury
Alkali worse than acid (penetrates rapidly); IMMEDIATE copious irrigation regardless of cause; urgent ophthalmology.
Source: RCOphth; AAO
Step 1 of ~3
info
Recognise + IMMEDIATE Irrigation
Sources:
• Alkali (worst — liquefactive necrosis, deep penetration): cleaning products, ammonia, concrete, lime, drain cleaners.
• Acid (coagulative necrosis, less deep): toilet bowl cleaner, battery acid, hydrofluoric acid (worst — see HF pathway).
• Solvents, gases.
Features: severe pain, photophobia, ↓ vision, lacrimation, blepharospasm, conjunctival redness, corneal cloudiness, limbal blanching (ischaemia — predicts severity).
#1 INTERVENTION: IRRIGATION — START NOW, ASK QUESTIONS LATER.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Glycine · Irrigation solution / amino acid
- Acetic Acid 0.5–1% Solution · Topical Antimicrobial — Pseudomonas
- Noradrenaline (Norepinephrine) · Vasopressor (Alpha-1 and Beta-1 Agonist)
- Tranexamic Acid (ICU/Trauma/Surgical) · Antifibrinolytic
- Acipimox · Lipid-modifying agent (Nicotinic acid derivative)
- Colesevelam hydrochloride · Bile acid sequestrant
Pathways
- Acute Red Eye / Vision Loss Screen · RCOphth 2020; NICE CKS
- Idiopathic Intracranial Hypertension · ABN; consensus 2018
- Acute Red Eye Assessment · RCOphth / AAO
- Acute Angle Closure Glaucoma · RCOphth / EGS Guidelines
- Retinal Detachment · RCOphth Guidelines / EURETINA
- Diabetic Retinopathy — Screening and Management · NICE NG28 2016 / NHS DES Programme
Decision support only. Always apply local guidelines and clinical judgement.