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Loop diuretic + potassium-sparing

Furosemide with triamterene

Brand names: Frusene

Adult dose

Dose: 1 tab (40mg furosemide / 50mg triamterene) OD; max 2 tabs/day
Route: PO
Frequency: OD

Clinical pearls

  • Heart failure where K+ retention desired

Contraindications

  • Hyperkalaemia
  • Severe renal impairment
  • Anuria
  • Addison's disease

Side effects

  • Hyperkalaemia
  • Hyponatraemia
  • Hyperuricaemia
  • Postural hypotension
  • Photosensitivity

Interactions

  • ACEi/ARB/spironolactone (hyperkalaemia)
  • NSAIDs
  • Lithium (toxicity)

Monitoring

  • U&E
  • Weight

Reference: BNF; https://bnf.nice.org.uk/drugs/furosemide-with-triamterene/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.