Betaxolol 0.5% Eye Drops

How it works

By blocking beta-adrenergic receptors in the ciliary body it reduces aqueous humour production, thereby lowering intraocular pressure.

Prescribing in practice

• Despite topical use and relative beta-1 selectivity, systemic absorption means it should be avoided in uncontrolled heart failure, marked bradycardia or heart block and used cautiously in reversible airways disease.
• It can mask the adrenergic warning signs of hypoglycaemia in people with diabetes.
• Apply pressure to the inner corner of the eye after instillation to limit systemic absorption.

Monitoring

Monitor intraocular pressure to confirm response and observe for systemic beta-blockade such as bradycardia or bronchospasm.

Counselling the patient

• Report wheeze, breathlessness, a slow pulse or dizziness.
• Brief stinging or blurred vision after drops is common and settles.
• Remove contact lenses before instillation and wait before reinserting.

Evidence & guidelines

Betaxolol eye drops are an established topical therapy for open-angle glaucoma and ocular hypertension as reflected in current prescribing references.